Publications


Title : Single Chain Observation on Collapse Transition in Giant DNA Induced by Negatively-Charged Polymer

Language: English
Type: Article
Authors: Yuta Ichiba and Kenichi Yoshikawa
Journal: Biochemical and Biophysical Research Communications
Volume: 242
Number: 2
Month: 1
Year: 1998
Actual year: 1998
Pages: 441-445
doi:   10.1006/bbrc.1997.7967
Abstract: Poly-glutamic acid, a polyanion, has been shown to induce the all-or-none collapse transition in individual duplex DNAs from an elongated coil into a collapsed compact state, through the observation of single chains by fluorescence microscopy. This experimental finding is discussed in relation to the change in the higher-order structure of DNAs in the cytoplasmic space induced by a change in the concentration of polyanions, such as mRNA, as a possible route for feedback in gene expression. (C) 1998 Academic Press.

"Single Chain Observation on Collapse Transition in Giant DNA Induced by Negatively-Charged Polymer"

Yuta Ichiba and Kenichi Yoshikawa, Biochemical and Biophysical Research Communications, 242, 441-445 (1998)