Publications


Title : Unbinding of lipid bilayers induced by osmotic pressure in relation to unilamellar vesicle formation

Language: English
Type: Article
Authors: Norifumi L. Yamada, Mafumi Hishida, Hideki Seto, Kanta Tsumoto and T. Yoshimura
Journal: Europhysics Letters
Volume: 80
Number: 4
Month: 10
Year: 2007
Actual year: 2007
doi:   10.1209/0295-5075/80/48002
Abstract: Small-angle X-ray scattering and phase-contrast microscopy experiments were performed to investigate the effect of osmotic pressure on vesicle formation in a dioleoyl- phosphatidylcholine (DOPC)/water/NaI system. The multi-lamellar structure of lipid bilayers is unstabilized when a lipid film with a sufficient amount of NaI is hydrated by pure water. It has been confirmed that this phenomenon is due to the effect of osmotic pressure induced by a hetero- geneous distribution of NaI molecules. This could be the origin of the unbinding of lipid bilayers to conform large uni-lamellar vesicles.

"Unbinding of lipid bilayers induced by osmotic pressure in relation to unilamellar vesicle formation"

Norifumi L. Yamada, Mafumi Hishida, Hideki Seto, Kanta Tsumoto and T. Yoshimura, Europhysics Letters, 80, (2007)