Publications


Title : Optical Transport of a Single Cell-Sized Liposome

Language: English
Type: Article
Authors: Masatoshi Ichikawa and Kenichi Yoshikawa
Journal: Applied Physics Letters
ISSN: 0003-6951
Volume: 79
Number: 27
Month: 12
Year: 2001
Actual year: 2001
Pages: 4598-4600
doi:   10.1063/1.1430026
Abstract: A closed phospholipid membrane vesicle, or giant liposome, with a diameter of similar to 10 mum, constitutes a model of a living cell. Since the phospholipid membrane is about 5 nm thick, it is extremely difficult to trap an individual giant liposome with a laser. We report here the intact transport of an individual cell-sized liposome using an infrared laser. It is shown that the optical attractive potential on a liposome with an inner solution of higher refractivity is about one order of magnitude greater than that of a liposome with the same solution both inside and outside. Since this cell-sized liposome is rather stable, the optical manipulation of liposomes could be useful for the realization of a mum-scaled laboratory for use in biochemistry and molecular biology. (C) 2001 American Institute of Physics.

"Optical Transport of a Single Cell-Sized Liposome"

Masatoshi Ichikawa and Kenichi Yoshikawa, Applied Physics Letters, 79, 4598-4600 (2001)