| Language: | English | 
|---|---|
| Type: | Article | 
| Authors: | Masatoshi Ichikawa and Kenichi Yoshikawa | 
| Journal: | Applied Physics Letters | 
| ISSN: | 0003-6951 | 
| Volume: | 79 | 
| Number: | 27 | 
| Month: | 12 | 
| Year: | 2001 | 
| Actual year: | 2001 | 
| Pages: | 4598-4600 | 
| doi: | 10.1063/1.1430026 | 
| Abstract: | A closed phospholipid membrane vesicle, or giant liposome, with a diameter of similar to 10 mum, constitutes a model of a living cell. Since the phospholipid membrane is about 5 nm thick, it is extremely difficult to trap an individual giant liposome with a laser. We report here the intact transport of an individual cell-sized liposome using an infrared laser. It is shown that the optical attractive potential on a liposome with an inner solution of higher refractivity is about one order of magnitude greater than that of a liposome with the same solution both inside and outside. Since this cell-sized liposome is rather stable, the optical manipulation of liposomes could be useful for the realization of a mum-scaled laboratory for use in biochemistry and molecular biology. (C) 2001 American Institute of Physics. | 
Masatoshi Ichikawa and Kenichi Yoshikawa, Applied Physics Letters, 79, 4598-4600 (2001)