| Language: | English |
|---|---|
| Type: | Article |
| Authors: | Kenichi Yamashita, Toshio Iwataki, Taizo Hatta, Kenichi Yoshikawa, Otohiko Tsuge, Makoto Takagi and Shigeori Takenaka |
| Journal: | Nucleic Acids Symposium Series |
| ISSN: | 1746-8272 |
| Volume: | 44 |
| Number: | 1 |
| Year: | 2000 |
| Actual year: | 2000 |
| Pages: | 173-174 |
| URL: | http://nass.oxfordjournals.org/cgi/content/abstract/44/1/173 |
| Abstract: | Cationic fullerene derivative 1, which is soluble in aqueous medium, bound to double stranded DNA. Observation of Coliphage T4 DNA in the absence and presence of 1 by fluorescence microscopy suggested that 1 bound to DNA along its groove. Upon irradiation of visible light on the DNA complex of 1, DNA was cleaved dramatically. The process of DNA photo-cleavage could be monitored continuously by fluorescence microscopy. |
Kenichi Yamashita, Toshio Iwataki, Taizo Hatta, Kenichi Yoshikawa, Otohiko Tsuge, Makoto Takagi and Shigeori Takenaka, Nucleic Acids Symposium Series, 44, 173-174 (2000)