Publications


Title : Molecular fabrication: Aligning DNA molecules as building blocks

Language: English
Type: Article
Authors: Masatoshi Ichikawa, Yukiko Matsuzawa, Yoshiyuki Koyama and Kenichi Yoshikawa
Journal: Langmuir
ISSN: 0743-7463
Volume: 19
Number: 13
Month: 6
Year: 2003
Actual year: 2003
Pages: 5444-5447
doi:   10.1021/la034338t
Abstract: We report here a novel method for assembling macromolecules in a sequential order. Individual DNA molecules can be prefabricated into a linear micrometer-sized pearling chain, or colored bar, under trapping with a focused IR laser, by using a suitable chemical agent, Chol-PEG-A (poly(ethylene glycol) with amino- and cholesteryl-pendant groups), to complex with DNA. Using the laser, these fabricated bars can then be pieced together into a complex structure. This approach could be useful for the further development of micromanufacture using macromolecules as nanoelements.

"Molecular fabrication: Aligning DNA molecules as building blocks"

Masatoshi Ichikawa, Yukiko Matsuzawa, Yoshiyuki Koyama and Kenichi Yoshikawa, Langmuir, 19, 5444-5447 (2003)