| Language: | English |
|---|---|
| Type: | Article |
| Authors: | Yuta Ichiba and Kenichi Yoshikawa |
| Journal: | Biochemical and Biophysical Research Communications |
| Volume: | 242 |
| Number: | 2 |
| Month: | 1 |
| Year: | 1998 |
| Actual year: | 1998 |
| Pages: | 441-445 |
| doi: | 10.1006/bbrc.1997.7967 |
| Abstract: | Poly-glutamic acid, a polyanion, has been shown to induce the all-or-none collapse transition in individual duplex DNAs from an elongated coil into a collapsed compact state, through the observation of single chains by fluorescence microscopy. This experimental finding is discussed in relation to the change in the higher-order structure of DNAs in the cytoplasmic space induced by a change in the concentration of polyanions, such as mRNA, as a possible route for feedback in gene expression. (C) 1998 Academic Press. |
Yuta Ichiba and Kenichi Yoshikawa, Biochemical and Biophysical Research Communications, 242, 441-445 (1998)