Language: | English |
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Type: | Article |
Authors: | Naoko Makita and Kenichi Yoshikawa |
Journal: | FEBS Letters |
ISSN: | 0014-5793 |
Volume: | 460 |
Number: | 2 |
Month: | 10 |
Year: | 1999 |
Actual year: | 1999 |
Pages: | 333-337 |
doi: | 10.1016/s0014-5793(99)01368-x |
Abstract: | In the living cellular environment, DNAs exist in a compact state in the presence of a polyamine, such as spermidine, We found that the hydrolysis of.-ITP into ADP induces the folding of elongated DNAs, by the single-chain observation of individual T4 DNA molecules, This result is discussed in relation to the possible role of ATP as a regulatory factor in genetic activity, in addition to its well-established role as an energy source, (C) 1999 Federation of European Biochemical Societies. |
Naoko Makita and Kenichi Yoshikawa, FEBS Letters, 460, 333-337 (1999)