| Language: | English |
|---|---|
| Type: | Article |
| Authors: | Akira Ohsaka, Kenichi Yoshikawa and Tyoku Matuhasi |
| Journal: | Japanese journal of medical science & biology |
| ISSN: | 0021-5112 |
| Volume: | 32 |
| Number: | 5 |
| Year: | 1979 |
| Actual year: | 1979 |
| Pages: | 305-309 |
| URL: | http://www.journalarchive.jst.go.jp/japanese/jnlabstract_ja.php?cdjournal=yoken1952&cdvol=32&noissue=5&startpage=305 |
| Abstract: | Proton nuclear magnetic resonance (1H-NMR) spectra of the serum specimens from patients with malignant tumors were compared with those from presumably healthy persons. We found that 87% of serum specimens from the patients yielded a common proton signal, which was ascribed to the methyl protons of lactic acid; whereas only 9% of serum specimens from the healthy persons tested gave this signal. On the basis of these results we concluded that the lactate level in the serum can be used as a criterion for the diagnosis of cancer in humans and that the determination of lactate concentration in the serum is easily performed by means of 1H-NMR. |
Akira Ohsaka, Kenichi Yoshikawa and Tyoku Matuhasi, Japanese journal of medical science & biology, 32, 305-309 (1979)