Publications

Title:
Thermo-Switching of the Conformation of Genomic DNA in Solutions of Poly (N-isopropylacrylamide)

Language:English
Type:Article
Authors:Ning Chen, Anatoly A. Zinchenko, Satoru Kidoaki, Shizuaki Murata and Kenichi Yoshikawa
Editors:
Journal:Langmuir
Volume:26
Number:5
Month:3
Year:2010
Actual year:2009
Pages:2995–2998
URL:http://pubs.acs.org/doi/abs/10.1021/la904375k
doi:10.1021/la904375k
bibtex id:2010_Langmuir_NChen_10-23
Abstract:
We used poly(N-isopropylacrylamide) (PNIPAM) to control the conformation of genomic DNA by changing the temperature of a reaction solution and studied the DNA transition at the level of single DNA molecules. With this method, the conformation of long genomic DNA can be readily and reversibly switched between a very compact condensate and an unfolded macromolecule.
Acknowledgment:
2010
"Thermo-Switching of the Conformation of Genomic DNA in Solutions of Poly (N-isopropylacrylamide)"
Ning Chen, Anatoly A. Zinchenko, Satoru Kidoaki, Shizuaki Murata and Kenichi Yoshikawa, Langmuir, 26(5), 2995–2998 (2010)
detail
publisher
doi:10.1021/la904375k