Publications

Title:
Fluorescence Microscopic Visualization of a DNA-Cationic Fullerene Complex

Language:English
Type:Article
Authors:Kenichi Yamashita, Toshio Iwataki, Taizo Hatta, Kenichi Yoshikawa, Otohiko Tsuge, Makoto Takagi and Shigeori Takenaka
Editors:
Journal:Nucleic Acids Symposium Series
ISSN:1746-8272
Volume:44
Number:1
Year:2000
Actual year:2000
Pages:173–174
URL:http://nass.oxfordjournals.org/cgi/content/abstract/44/1/173
bibtex id:2000_NASS_Yamashita_00-11
Abstract:
Cationic fullerene derivative 1, which is soluble in aqueous medium, bound to double stranded DNA. Observation of Coliphage T4 DNA in the absence and presence of 1 by fluorescence microscopy suggested that 1 bound to DNA along its groove. Upon irradiation of visible light on the DNA complex of 1, DNA was cleaved dramatically. The process of DNA photo-cleavage could be monitored continuously by fluorescence microscopy.
Acknowledgment:
2000
"Fluorescence Microscopic Visualization of a DNA-Cationic Fullerene Complex"
Kenichi Yamashita, Toshio Iwataki, Taizo Hatta, Kenichi Yoshikawa, Otohiko Tsuge, Makoto Takagi and Shigeori Takenaka, Nucleic Acids Symposium Series, 44(1), 173–174 (2000)
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