Publications


Title : Thermo-Switching of the Conformation of Genomic DNA in Solutions of Poly (N-isopropylacrylamide)

Language: English
Type: Article
Authors: Ning Chen, Anatoly A. Zinchenko, Satoru Kidoaki, Shizuaki Murata and Kenichi Yoshikawa
Journal: Langmuir
Volume: 26
Number: 5
Month: 3
Year: 2010
Actual year: 2009
Pages: 2995-2998
URL:   http://pubs.acs.org/doi/abs/10.1021/la904375k
doi:   10.1021/la904375k
Abstract: We used poly(N-isopropylacrylamide) (PNIPAM) to control the conformation of genomic DNA by changing the temperature of a reaction solution and studied the DNA transition at the level of single DNA molecules. With this method, the conformation of long genomic DNA can be readily and reversibly switched between a very compact condensate and an unfolded macromolecule.

"Thermo-Switching of the Conformation of Genomic DNA in Solutions of Poly (N-isopropylacrylamide)"

Ning Chen, Anatoly A. Zinchenko, Satoru Kidoaki, Shizuaki Murata and Kenichi Yoshikawa, Langmuir, 26, 2995-2998 (2010)