| Language: | English |
|---|---|
| Type: | Article |
| Authors: | Ning Chen, Anatoly A. Zinchenko, Satoru Kidoaki, Shizuaki Murata and Kenichi Yoshikawa |
| Journal: | Langmuir |
| Volume: | 26 |
| Number: | 5 |
| Month: | 3 |
| Year: | 2010 |
| Actual year: | 2009 |
| Pages: | 2995-2998 |
| URL: | http://pubs.acs.org/doi/abs/10.1021/la904375k |
| doi: | 10.1021/la904375k |
| Abstract: | We used poly(N-isopropylacrylamide) (PNIPAM) to control the conformation of genomic DNA by changing the temperature of a reaction solution and studied the DNA transition at the level of single DNA molecules. With this method, the conformation of long genomic DNA can be readily and reversibly switched between a very compact condensate and an unfolded macromolecule. |
Ning Chen, Anatoly A. Zinchenko, Satoru Kidoaki, Shizuaki Murata and Kenichi Yoshikawa, Langmuir, 26, 2995-2998 (2010)